Hedex Contains Paracetamol Which Is An Effective Antipyretic And Analgesic. Produces Antipyresis By Acting On The Hypothalamic Heat Regulating Center And Analgesia By Elevating The Pain Threshold. Aspirin Has Analgesic ,Anti Inflammatory And Anti Pyretic Actions. Aspirin Acts By Inhibiting The Enzyme Cyclooxygenase, Which Results In The Inhibition Of Biosynthesis Of Prostaglandins. Prostaglandins Are Associated With The Development Of Pain That Accompanies Injury Or Inflammation. Enhanced Production Of Prostaglandins Is A Common Feature In Fever.
Caffeine In Lower Doses Stimulates The Cns And This Imparts A Synergistic Effect To The Aspirin And Paracetamol Combination.
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